Clinical trials landscape in the UK

Numbers of patients enrolled onto commercially-led ​studies supported by the NIHR dropped by 44% between ​2017 to 2018 and 2021 to 2022, from around 50,000 a ​year to around 28,000.

The number of trials initiated dropped from 4th to 10th best in ​the world in the same timeframe. Other countries like Poland, ​have been able to recruit high numbers of patients for each ​commercial trial, with an average of 61 participants in Phase 2 ​and 3 trials compared to an average of 21 per trial in the UK ​between 2018 and 2020


In response, UK Government commissioned Lord James O’Shaughnessy Report published on 26 May 2023 sets out 27 ​recommendations intended to deliver major, sustained growth in commercial trial activity.

The report sets a goal of doubling patients enrolled in commercial studies ​by 2025 and doubling the number again by 2027. Medica research ​addresses one of the key issues to meeting this target


The report also states that primary care is a negligible provider of clinical ​trial activity, despite the opportunities it provides for delivering ​population-scale trials, and there is too much reliance on hospital settings ​for the delivery of trials.


Delivering quality ​research in primary care